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Reading the research
Clinical trial phases and registrations
What phase 1, 2 and 3 mean, and why a registered trial isn't a result.
- Phase 1: usually 20 to 80 people; is it safe, and how does the body handle it?
- Phase 2: up to a few hundred people with the condition; does it seem to work, at what amounts, with what side effects?
- Phase 3: hundreds to thousands of people, usually randomized against placebo or standard treatment; the evidence regulators approve drugs on.
Trials are registered on ClinicalTrials.gov before they start. A registration tells you a study exists, its design and status. It isn't a result: many trials finish without publishing, and "recruiting" means it hasn't produced evidence yet. Look for posted results or a published paper.
Key points
- Phase 3 trials are the basis for approval.
- Registered ≠ results.
- Check whether results were posted or published.
Quick check
A peptide has 3 trials 'recruiting' on ClinicalTrials.gov. What does that tell you about whether it works?
Recruiting trials haven't produced results.
Clinical trials for every peptide
Sources
General education, not medical advice. Nothing here recommends using any compound or amount.