Klotho
Klotho is a kidney-made protein whose soluble form regulates phosphate, FGF23 signalling and oxidative stress; low levels track with aging. Raising it extends lifespan and improves cognition in mice; no human trials of supplementation.
Not approved. Research use only.
Look it up on Wikipedia7 listings across 3 independently tested vendors, ranked by price per milligram after coupon codes anyone can use. Vendors you can only order from by message are hidden.
Daily price tracking started October 7, 2026; a price-history chart appears here once a few days have been collected.
| Vendor | Trust | Listing | Vials | Price | Per mg | |
|---|---|---|---|---|---|---|
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Klotho (alphaKlothoLR) (20mcg) 1 Pair (2 Vials) | 2 × 20 mcg = 0.04 mg | $299.00 $149.50 per vial |
$7,475.00 | Buy |
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Klotho (alphaKlothoLR) (20mcg) 6 Pairs (12 Vials) – Save 5% | 12 × 20 mcg = 0.24 mg | $1,794.00 $149.50 per vial |
$7,475.00 | Buy |
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Klotho (alphaKlothoLR) (20mcg) 12 Pairs (24 Vials) – Save 10% | 24 × 20 mcg = 0.48 mg | $3,588.00 $149.50 per vial |
$7,475.00 | Buy |
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Klotho (alphaKlothoLR) (20mcg) 24 Pairs (48 Vials) – Save 15% | 48 × 20 mcg = 0.96 mg | $7,176.00 $149.50 per vial |
$7,475.00 | Buy |
Alpha BioMed #281 by metascore · US |
a-Klotho LR (10mcg) | 1 × 10 mcg | $105.00 | $10,500.00 | Buy | |
Peptagon #31 by metascore |
Metascore 82 medium confidenceFinnrick UnratedBought vials 102% of label · 3 testsTitrateLabNo report for thisConfirmed with lab: 38 of 38Online checkout |
α-Klotho Monoclonal Research Antibody – 10mcg – 2 Vials | 2 × 10 mcg = 0.02 mg | $631.00 $315.50 per vial |
$31,550.00 | Buy |
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Klotho (alphaKlothoLR) (Single Vial) | 1 vial, size not stated | $250.00 | – | Buy |
Mixing a 0.02 mg vial
What each common amount of bacteriostatic water gives you on a U-100 insulin syringe. Pick a vial size above to change it.
| Water | Strength | Per 10 units (0.1 mL) | Per unit |
|---|---|---|---|
| 1 mL | 0.02 mg/mL | 2 mcg | 0.2 mcg |
| 2 mL | 0.01 mg/mL | 1 mcg | 0.1 mcg |
| 3 mL | 0.007 mg/mL | 0.7 mcg | 0.07 mcg |
| 5 mL | 0.004 mg/mL | 0.4 mcg | 0.04 mcg |
Discussions elsewhere
Experiences and questions about Klotho on other sites. Treat anecdotes with care.
Klotho: questions people ask
What is Klotho?
Anti-aging protein. Klotho is a kidney-made protein whose soluble form regulates phosphate, FGF23 signalling and oxidative stress; low levels track with aging. Raising it extends lifespan and improves cognition in mice; no human trials of supplementation.
How much does Klotho cost?
The cheapest Klotho from an independently tested vendor is $7,475.00 per mg (Biolongevity Labs, Klotho (alphaKlothoLR) (20mcg) 1 Pair (2 Vials), $299.00). Across 7 listings from 3 vendors the median is $7,475.00 per mg.
Where can I buy Klotho?
3 vendors tested by Finnrick sell Klotho. The cheapest per mg right now: Biolongevity Labs ($7,475.00), Alpha BioMed ($10,500.00), Peptagon ($31,550.00). 0 of them publish a lab report (COA) for Klotho; compare lab scores and reports in the table above before buying.
Is Klotho FDA approved?
Not approved. Research use only.