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Lemon Bottle research

What published studies found for Lemon Bottle: 3 papers, 0 in humans, with sample sizes and key results.

D
Little or no evidence
Why: No published studies of Lemon Bottle itself; only reviews and case reports on other unlicensed fat-dissolving injections.

No peer-reviewed studies of the 'Lemon Bottle' fat-dissolving product were found in PubMed. The only related literature covers other unlicensed fat-dissolving (injection lipolysis/mesotherapy) products, where reviews call efficacy unproven and case reports describe infections and other complications.

✗ 2 negative? 1 inconclusive

No human safety data on Lemon Bottle itself; reports for other unlicensed fat-dissolving injections include mycobacterial infections and one case of ARDS.

Browse and filter these papersLemon Bottle prices and vendors

Reviews

? InconclusivereviewAesthetic Plast Surg · 2008

Cosmetic mesotherapy: between scientific evidence, science fiction, and lucrative business.

No new dataNarrative review

Review of cosmetic mesotherapy and 'fat-dissolving' injections: safety and efficacy remain ambiguous and more studies are needed before they can be advocated.

Studied
Cosmetic mesotherapy (narrative review)
Authors' conclusion
The safety and efficacy of mesotherapy remain ambiguous; more studies are necessary before it can be advocated for body contouring and facial rejuvenation.
Limitations
Narrative review with no original data.
PubMed 18663517DOI
✗ NegativereviewJ Cosmet Dermatol · 2023

Skin and soft tissue infection of Nontuberculous mycobacterium after injection lipolysis.

No new dataLiterature review (Medline and PubMed up to September 2022)

Literature review of nontuberculous mycobacterial skin infections after injection lipolysis, linked to poor sterility, unqualified products and the procedure itself; diagnosis and treatment are difficult. Not specific to Lemon Bottle.

Studied
Patients with nontuberculous mycobacterium skin and soft tissue infection after injection lipolysis
Main outcome
Association between NTM infection and injection lipolysis
Authors' conclusion
NTM infection after injection lipolysis may relate to inadequate disinfection, unqualified products and released free fatty acids; strict aseptic standards and qualified products are needed.
Limitations
Literature review.
PubMed 36606392DOI

Human studies

✗ Negativecase reportAm J Case Rep · 2026

Possible ARDS Following Cosmetic Lipolysis: A Case Report Urging Caution in Aesthetic Medicine.

Single case report (41-year-old woman)Case report

A healthy 41-year-old developed acute respiratory distress syndrome within 30 minutes of multiple lipolysis injections at an unlicensed facility; product not identified as Lemon Bottle.

Studied
Previously healthy woman with ARDS after lipolysis injections at an unlicensed facility
Main outcome
Respiratory complication after lipolysis injections
Authors' conclusion
ARDS is a rare but serious complication of cosmetic fat-dissolving injections; microscopic fat embolism remains a plausible mechanism.
Limitations
Single case.
PubMed 41721501DOIFree full text

Verdicts are judged on each paper's own main outcome; grades run from A (strong human evidence) to D (little or none). Details are read from the abstracts, and figures are reproduced only from openly licensed full texts. Not medical advice.