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KPV vs LL-37

KPV: Anti-inflammatory tripeptide. LL-37: Human antimicrobial peptide. Per milligram, KPV is cheaper right now (USD 0.500 vs USD 1.05 at the cheapest tested vendor). LL-37 has stronger published evidence (grade B vs C). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

KPV

The last three amino acids of alpha-MSH (lysine-proline-valine). Calms inflammatory signaling in cell and animal studies, notably in models of colitis and skin inflammation.

What it is
Anti-inflammatory tripeptide
Category
Inflammation & immune
Status
Not approved. Research use only.
Cheapest
USD 0.500 per mg (Uther)
Median price
USD 3.14 per mg
Vendors
78 independently tested, 31 with a lab report
Research
Grade C: Mostly animal studies (9 papers)
Studied as
tested only in animals or cells

LL-37

The only human cathelicidin: kills bacteria, fungi and some viruses and helps wound healing, but can also drive inflammation at high levels.

What it is
Human antimicrobial peptide
Category
Inflammation & immune
Status
Not approved. Research use only.
Cheapest
USD 1.05 per mg (Mai Peptide)
Median price
USD 7.04 per mg
Vendors
48 independently tested, 5 with a lab report
Research
Grade B: Some human evidence (8 papers)
Studied as
studied in people
Reported side effects
Wart-like / keratoacanthoma-like skin lesions after injection into tumors

Cheapest tested vendors for KPV and LL-37

Lowest price per milligram at up to three independently tested vendors each. Rankings are by price only; open a vendor to see its lab results.

PeptideVendorPer mg
KPVUtherUSD 0.500
Huaian Dinglin TradingUSD 0.550
Shenzhen Loga Tech LG LOGAUSD 0.550
LL-37Mai PeptideUSD 1.05
BeiBangAnUSD 1.50
Huaian Dinglin TradingUSD 1.50

Questions people ask

What is the difference between KPV and LL-37?

KPV: Anti-inflammatory tripeptide. LL-37: Human antimicrobial peptide. Per milligram, KPV is cheaper right now (USD 0.500 vs USD 1.05 at the cheapest tested vendor). LL-37 has stronger published evidence (grade B vs C). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

Which is cheaper, KPV or LL-37?

KPV is cheaper per mg: USD 0.500 for KPV vs USD 1.05 for LL-37 at the cheapest independently tested vendor. The median listing is USD 3.14 per mg for KPV and USD 7.04 per mg for LL-37.

Which is easier to find from a tested vendor, KPV or LL-37?

KPV is sold by more independently tested vendors: 78 list KPV (31 publish a lab report for it) and 48 list LL-37 (5 with a lab report).

Which has more published research, KPV or LL-37?

KPV is graded C (mostly animal studies) from 9 papers and LL-37 is graded B (some human evidence) from 8 papers. Grades count studies of the exact compound only; they describe how much evidence exists, not which one is better.

Are KPV and LL-37 FDA approved?

KPV: Not approved. Research use only. LL-37: Not approved. Research use only.

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