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Sermorelin vs Tesamorelin

Sermorelin: GHRH analog (GHRH 1-29). Tesamorelin: GHRH analog. Per milligram, Tesamorelin is cheaper right now ($1.05 vs $1.05 at the cheapest tested vendor). Tesamorelin has stronger published evidence (grade A vs B). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

Sermorelin

The first 29 amino acids of growth-hormone-releasing hormone; stimulates the pituitary to release growth hormone.

What it is
GHRH analog (GHRH 1-29)
Category
Growth hormone
Status
Was FDA-approved (Geref) for growth-hormone deficiency in children; the brand was discontinued. Available through compounding.
Cheapest
$1.05 per mg (Andy Peps Studio)
Median price
$4.24 per mg
Vendors
75 independently tested, 15 with a lab report
Research
Grade B: Some human evidence (8 papers)
Studied as
studied in people
Reported side effects
Anti-GHRH antibody formation; Transient facial flushing; Injection-site pain or irritation; Transient hyperlipidemia (with a related GHRH(1-29) analog)

Tesamorelin

A stabilized growth-hormone-releasing hormone that raises the body's own growth hormone and reduces visceral belly fat.

What it is
GHRH analog
Category
Growth hormone
Status
FDA-approved as Egrifta for abdominal fat in HIV-associated lipodystrophy.
Cheapest
$1.05 per mg (Andy Peps Studio)
Median price
$4.77 per mg
Vendors
99 independently tested, 43 with a lab report
Research
Grade A: Strong human evidence (8 papers)
Studied as
an approved drug
Reported side effects
Injection-site reactions (e.g., erythema); Arthralgia (joint pain); Myalgia (muscle pain); Paresthesia

Questions people ask

What is the difference between Sermorelin and Tesamorelin?

Sermorelin: GHRH analog (GHRH 1-29). Tesamorelin: GHRH analog. Per milligram, Tesamorelin is cheaper right now ($1.05 vs $1.05 at the cheapest tested vendor). Tesamorelin has stronger published evidence (grade A vs B). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

Which is cheaper, Sermorelin or Tesamorelin?

Tesamorelin is cheaper per mg: $1.05 for Sermorelin vs $1.05 for Tesamorelin at the cheapest independently tested vendor.