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Ipamorelin vs Sermorelin

Ipamorelin: Selective growth-hormone secretagogue. Sermorelin: GHRH analog (GHRH 1-29). Per milligram, Ipamorelin is cheaper right now ($0.500 vs $1.05 at the cheapest tested vendor). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

Ipamorelin

A five-amino-acid ghrelin-receptor agonist that triggers a growth-hormone pulse with little effect on cortisol or prolactin in studies.

What it is
Selective growth-hormone secretagogue
Category
Growth hormone
Status
Not approved. Research use only; prohibited in sport.
Cheapest
$0.500 per mg (Nantong Guangyuan Chemical GYC)
Median price
$3.80 per mg
Vendors
87 independently tested, 22 with a lab report
Research
Grade B: Some human evidence (8 papers)
Studied as
studied in people

Sermorelin

The first 29 amino acids of growth-hormone-releasing hormone; stimulates the pituitary to release growth hormone.

What it is
GHRH analog (GHRH 1-29)
Category
Growth hormone
Status
Was FDA-approved (Geref) for growth-hormone deficiency in children; the brand was discontinued. Available through compounding.
Cheapest
$1.05 per mg (Andy Peps Studio)
Median price
$4.24 per mg
Vendors
75 independently tested, 15 with a lab report
Research
Grade B: Some human evidence (8 papers)
Studied as
studied in people
Reported side effects
Anti-GHRH antibody formation; Transient facial flushing; Injection-site pain or irritation; Transient hyperlipidemia (with a related GHRH(1-29) analog)

Questions people ask

What is the difference between Ipamorelin and Sermorelin?

Ipamorelin: Selective growth-hormone secretagogue. Sermorelin: GHRH analog (GHRH 1-29). Per milligram, Ipamorelin is cheaper right now ($0.500 vs $1.05 at the cheapest tested vendor). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.

Which is cheaper, Ipamorelin or Sermorelin?

Ipamorelin is cheaper per mg: $0.500 for Ipamorelin vs $1.05 for Sermorelin at the cheapest independently tested vendor.