Bronchogen
One of the Khavinson "bioregulator" peptides from Russian aging research, marketed for the bronchi and lungs. Evidence comes mainly from Russian cell and animal studies.
Sold as a supplement in Russia; not approved in the US. Research use only.
Look it up on Wikipedia14 listings across 13 independently tested vendors, ranked by price per milligram after coupon codes anyone can use. Vendors you can only order from by message are hidden.
Some links here are affiliate links: if you buy through one, this site may earn a commission at no extra cost to you. Prices, rankings and plans are worked out the same way whether or not a vendor pays one.
Not an FDA-approved drug and not nominated for FDA's 503A bulks list, so US pharmacies can't legally compound it.
Daily price tracking started October 7, 2026; a price-history chart appears here once a few days have been collected.
| Vendor | Trust | Listing | Vials | Price | Per mg | |
|---|---|---|---|---|---|---|
Uther #62 by metascore · China |
Metascore 79Finnrick 64%Bought vials 105% of label · 73 testsTitrateLabNo report for thisOnline checkout |
Bronchogen 20mg (10 Vials / Kit) | 10 × 20 mg = 200 mg | $150.00 $15.00 per vial |
$0.750 | Buy |
Qingdao Sigma Chemical QSC #69 by metascore |
Bronchogen 20mg | 20-Vial Kit | Lung Tissue Peptide Bioregulator | 20 × 20 mg = 400 mg | $470.00 $23.50 per vial |
$1.18 | Buy | |
Bulk Peptide Wholesale #29 by metascore |
Metascore 82 medium confidenceFinnrick 68%Bought vials 103% of label · 7 testsTitrateLab · PeptideBaseNo report for thisOnline checkout |
Bronchogen 20 mg (10 vials) | 10 × 20 mg = 200 mg | $250.00 $25.00 per vial |
$1.25 | Buy |
Qingdao Sigma Chemical QSC #69 by metascore |
Bronchogen 20mg | 10-Vial Kit | Lung Tissue Peptide Bioregulator | 10 × 20 mg = 200 mg | $260.00 $26.00 per vial |
$1.30 | Buy | |
Nexaph #90 by metascore |
Metascore 76Finnrick 57%PepIndex 19/100Bought vials 109% of label · 285 testsTitrateLab · PeptideBaseNo report for thisOnline checkout |
Bronchogen 10mg (10 vials/kit) | 10 × 10 mg = 100 mg | $158.00 $15.80 per vial |
$1.58 | Buy |
Eros Peptides #129 by metascore · US, GA 30339 |
Metascore 74 medium confidenceFinnrick 77%Bought vials 110% of label · 3 testsTitrateLab · Peptide CriticLab report (image)Online checkout |
Bronchogen 20MG | 1 × 20 mg | $33.99 | $1.70 | Buy |
Amino Usa #136 by metascore · US |
Metascore 74 medium confidenceFinnrick 32%Bought vials 89% of label · 3 testsTitrateLabLab 99.7% pure · 102% of labelAccount needed |
Bronchogen 20mg | 1 × 20 mg | $50.00 | $2.50 | Buy |
Modern Aminos Affiliate #125 by metascore · US |
Metascore 75 medium confidenceFinnrick 79%PepIndex 81/100Bought vials 100% of label · 5 testsTitrateLab · PeptideBase · Peptide CriticNo report for thisOnline checkout |
BRONCHOGEN 20MG $30 off through this site's link (new customers) |
1 × 20 mg | $54.00 $30 off through this site's link (new customers) |
$2.70 | Buy |
Lab Rat Peptide #206 by metascore · US |
Bronchogen 20MG | 1 × 20 mg | $55.00 | $2.75 | Buy | |
Amino Asylum #245 by metascore |
Metascore 71Finnrick 62%PepIndex 26/100Bought vials 100% of label · 15 testsTitrateLab · PeptideBaseNo report for thisOnline checkout |
Bronchogen 20MG | 1 × 20 mg | $64.99 | $3.25 | Buy |
Core Peptides #282 by metascore |
Metascore 70 medium confidenceFinnrick 76%PepIndex 24/100Bought vials 92% of label · 4 testsTitrateLab · PeptideBase · Peptide Critic · PeptideCheckedLab 99.1% pureOnline checkout |
Bronchogen – 20MG | 1 × 20 mg | $68.00 | $3.40 | Buy |
Biolongevity Labs #166 by metascore · US, Akron, OH 44321 |
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout |
Bronchogen (20mg) | 1 × 20 mg | $69.97 | $3.50 | Buy |
Certified Peptides #66 by metascore · US, WA 98579 |
Metascore 79Finnrick 58%Bought vials 100% of label · 12 testsTitrateLabNo report for thisOnline checkout |
BRONNCHGEN 20MG | 1 × 20 mg | $105.00 | $5.25 | Buy |
Amplified Amino Affiliate #27 by metascore · US: TX 78248 |
Metascore 83Finnrick 65%Bought vials 115% of label · 12 testsTitrateLabNo report for thisOnline checkout |
Bronchogen 10mg | 1 × 10 mg | $58.00 | $5.80 | Buy |
Mixing a 20 mg vial
What each common amount of bacteriostatic water gives you on a U-100 insulin syringe. Pick a vial size above to change it.
| Water | Strength | Per 10 units (0.1 mL) | Per unit |
|---|---|---|---|
| 1 mL | 20 mg/mL | 2,000 mcg | 200 mcg |
| 2 mL | 10 mg/mL | 1,000 mcg | 100 mcg |
| 3 mL | 6.667 mg/mL | 666.7 mcg | 66.67 mcg |
| 5 mL | 4 mg/mL | 400 mcg | 40 mcg |
Published lab results
5 certificates of analysis that vendors publish for Bronchogen. Numbers are only filled in where the document is readable text; image-only COAs are linked without numbers. A vendor's own COA shows one tested sample, not every batch.
| Vendor | Lab | Date | Label | Measured | Purity | Batch | |
|---|---|---|---|---|---|---|---|
Bulk Peptide SupplyCOA concerns Most reports come from AV Analytics, a lab with no website or lookup to verify them, and they all read 99.73-99.81% purity across 19 different peptides and blends; its MDx reports are similarly uniform. Eight others are issued to 'Peptide COA Test LLC'. Checked 2026-10-08. How we check |
AV Analytics | 2026-09-06 | 20 mg | – | 99.77% | BRN208892 | View |
Ion Peptide |
Freedom Diagnostics ✓ lab | 2026-09-05 | 20 mg | 19.93 mg 100% | 99.4% | BRN20-09022026 | View |
Amino Usa |
BioRegen | 2026-09-01 | 20 mg | 20.47 mg 102% | 99.71% | 26BRON20-0005 | View |
Core Peptides |
Vanguard Laboratory | 2026-08-21 | 20 mg | – | 99.1% | C73555 | View |
Eros PeptidesCOA note |
Janoshik | – | 20 mg | – | – | View (image) |
Doses studied in research Animal or lab studies only
What was given to people (or animals) in published studies and official labels, each linked to its source. This is not a recommendation: study products, purity and supervision differ from research-grade vials.
Animal studies: Rats with NO2-induced COPD-like lung damage received bronchogen for 1 month (dose not stated in the abstracts); tissue-culture studies used 0.05 ng/ml; other work is in cell lines, DNA and tobacco plants.
No human studies were found; nearly all research comes from the developer's group. Doses in animal studies do not translate directly to people.
What the research says
Bronchogen (Ala-Glu-Asp-Leu, AEDL) is a St. Petersburg 'peptide bioregulator' marketed for the lungs; the evidence is two small rat COPD-model studies plus cell, DNA and even plant experiments, nearly all from the developer's network. No human studies were found.
Key papers ✓ 2? 3
-
Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology.Animalssize not reported1 month of treatmentTetrapeptide Bronchogen therapy in a rat COPD model
In rats with NO2-induced COPD-like lung damage, one month of Bronchogen reportedly reversed bronchial epithelial remodeling (goblet cell hyperplasia, metaplasia, emphysema), increased secretory IgA and reduced neutrophilic inflammation.
Study details
- Studied
- Rats with COPD modeled by 60-day intermittent NO2 exposure
- Main outcome
- Bronchial epithelium remodeling, secretory IgA, cytokines
- Authors' conclusion
- One month of Bronchogen eliminated signs of bronchial epithelium and lung remodeling, raised secretory IgA and normalized cell composition and proinflammatory cytokines, reflecting reduced neutrophilic inflammation.
- Limitations
- Rat model; sample size not stated in abstract.
-
[ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY].Animalssize not reportedBronchogen course with bronchoalveolar lavage analysis
Same rat COPD model: Bronchogen normalized lavage-fluid cell composition and pro-inflammatory cytokines and raised secretory IgA and surfactant protein B.
Study details
- Studied
- Rats with COPD modeled by 60-day intermittent nitrogen dioxide exposure
- Main outcome
- BALF cell composition, cytokines, secretory IgA, surfactant protein B
- Authors' conclusion
- Peptide treatment reduced neutrophilic inflammation, restored bronchial epithelium structure and increased secretory IgA and surfactant protein B.
- Limitations
- Rat model; sample size not stated in abstract.
-
Peptides tissue-specifically stimulate cell differentiation during their aging.Cells / labIn vitro expression study in young and late-passage (aging) cultures
In aging human bronchial epithelial cell cultures, Bronchogen stimulated expression of differentiation factors CXCL12 and Hoxa3.
Study details
- Studied
- Human embryonic pancreatic and bronchial cells and prostatic fibroblasts in culture
- Main outcome
- Expression of CXCL12, Hoxa3 and WEGC1 differentiation factors
- Authors' conclusion
- Vesugen stimulated differentiation factor expression in fibroblasts, with a stronger effect in aged cultures, which may be a mechanism of geroprotective effect.
- Limitations
- In vitro cell culture only.
-
Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.Cells / labIn vitro gene expression and promoter DNA-methylation analysis with KEDW and AEDL peptides
In aging bronchial cell cultures, AEDL altered expression of several lung genes (e.g. NKX2-1, SCGB1A1), possibly via promoter methylation changes; other genes were unaffected.
Study details
- Studied
- Ageing human pancreatic and bronchial epithelium cell cultures
- Compared with
- Untreated cultures of different age
- Main outcome
- Gene expression and promoter methylation of PDX1, PAX6, NGN3 and other genes
- Authors' conclusion
- Changes in promoter methylation might explain the age- and peptide-induced changes in expression of PDX1, PAX6 and NGN3 in pancreatic cells; other genes appear controlled by other mechanisms.
- Limitations
- Cell cultures only; mechanism, not efficacy.
-
Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability.No new dataDifferential scanning microcalorimetry of DNA melting with bronchogen
Calorimetry study: Bronchogen raised the melting temperature of isolated DNA by 3.1 °C, acting as a DNA-stabilizing agent.
Key resultBronchogen increased the melting temperature of DNA by 3.1°C in a narrow range of molar ratios
Study details
- Studied
- DNA from calf thymus and mouse liver
- Main outcome
- DNA melting temperature and enthalpy
- Authors' conclusion
- Bronchogen acts as a DNA-stabilizing agent, not specific for AT or GC pairs, binding strongly and occasionally to both strands.
- Limitations
- Biophysical in vitro study.
Reported side effects
No human safety or efficacy data in the published literature.
✓ positive · ✗ negative · ~ mixed · ? inconclusive, judged on each paper's own main outcome. Grades: A strong human evidence → D little or none. Papers and verdicts are drawn from PubMed, Europe PMC and Russian journals (CyberLeninka); not medical advice.
Discussions elsewhere
Experiences and questions about Bronchogen on other sites. Treat anecdotes with care.
Bronchogen: questions people ask
What is Bronchogen?
Russian short-peptide bioregulator. One of the Khavinson "bioregulator" peptides from Russian aging research, marketed for the bronchi and lungs. Evidence comes mainly from Russian cell and animal studies.
How much does Bronchogen cost?
The cheapest Bronchogen from an independently tested vendor is $0.750 per mg (Uther, Bronchogen 20mg (10 Vials / Kit), $150.00). Across 14 listings from 13 vendors the median is $2.70 per mg.
Where can I buy Bronchogen?
13 vendors tested by Finnrick sell Bronchogen. The cheapest per mg right now: Uther ($0.750), Qingdao Sigma Chemical QSC ($1.18), Bulk Peptide Wholesale ($1.25). 2 of them publish a lab report (COA) for Bronchogen; compare lab scores and reports in the table above before buying.
How much bacteriostatic water for 20 mg of Bronchogen?
Adding 2 mL of bacteriostatic water to a 20 mg vial of Bronchogen gives 10 mg/mL: each 10 units on a U-100 insulin syringe holds 1,000 mcg. With 1 mL it's 20 mg/mL (2,000 mcg per 10 units); with 3 mL, 6.667 mg/mL (666.7 mcg per 10 units). More water makes small amounts easier to measure. Mixing charts: 10 mg, 20 mg.
Is Bronchogen FDA approved?
Sold as a supplement in Russia; not approved in the US. Research use only.
Can Bronchogen be compounded in the US?
Not an FDA-approved drug and not nominated for FDA's 503A bulks list, so US pharmacies can't legally compound it. Compounding status for every peptide.
Does Bronchogen work? What does the research say?
Evidence grade C (mostly animal studies), from 5 papers: No human studies; two rat COPD-model studies from the developer's group plus cell, DNA and plant experiments. Bronchogen (Ala-Glu-Asp-Leu, AEDL) is a St. Petersburg 'peptide bioregulator' marketed for the lungs; the evidence is two small rat COPD-model studies plus cell, DNA and even plant experiments, nearly all from the developer's network. No human studies were found. See the papers.
What dose of Bronchogen was used in studies?
Bronchogen is tested only in animals or cells. Rats with NO2-induced COPD-like lung damage received bronchogen for 1 month (dose not stated in the abstracts); tissue-culture studies used 0.05 ng/ml; other work is in cell lines, DNA and tobacco plants. These are amounts used in published studies or official labels, not a recommendation.









