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Bronchogen

Longevity & bioregulators
Russian short-peptide bioregulator

One of the Khavinson "bioregulator" peptides from Russian aging research, marketed for the bronchi and lungs. Evidence comes mainly from Russian cell and animal studies.

Sold as a supplement in Russia; not approved in the US. Research use only.

Look it up on Wikipedia

14 listings across 13 independently tested vendors, ranked by price per milligram after coupon codes anyone can use. Vendors you can only order from by message are hidden.

Cheapest right now
$0.750 per mg
Uther
Bronchogen 20mg (10 Vials / Kit)
$150.00 for 10 × 20 mg = 200 mg
Metascore 79Finnrick 64%Bought vials 105% of label · 73 testsTitrateLabNo report for thisOnline checkout
Go to utherpeptide.com

Some links here are affiliate links: if you buy through one, this site may earn a commission at no extra cost to you. Prices, rankings and plans are worked out the same way whether or not a vendor pays one.

US compoundingNot compoundable

Not an FDA-approved drug and not nominated for FDA's 503A bulks list, so US pharmacies can't legally compound it.

Daily price tracking started October 7, 2026; a price-history chart appears here once a few days have been collected.

VendorTrustListingVialsPricePer mg
Uther
#62 by metascore · China
Metascore 79Finnrick 64%Bought vials 105% of label · 73 testsTitrateLabNo report for thisOnline checkout
Bronchogen 20mg (10 Vials / Kit) 10 × 20 mg = 200 mg $150.00
$15.00 per vial
$0.750 Buy
Qingdao Sigma Chemical QSC
#69 by metascore
Metascore 78Finnrick 64%Bought vials 103% of label · 47 testsNo report for thisOnline checkout
Bronchogen 20mg | 20-Vial Kit | Lung Tissue Peptide Bioregulator 20 × 20 mg = 400 mg $470.00
$23.50 per vial
$1.18 Buy
Bulk Peptide Wholesale
#29 by metascore
Metascore 82 medium confidenceFinnrick 68%Bought vials 103% of label · 7 testsTitrateLab · PeptideBaseNo report for thisOnline checkout
Bronchogen 20 mg (10 vials) 10 × 20 mg = 200 mg $250.00
$25.00 per vial
$1.25 Buy
Qingdao Sigma Chemical QSC
#69 by metascore
Metascore 78Finnrick 64%Bought vials 103% of label · 47 testsNo report for thisOnline checkout
Bronchogen 20mg | 10-Vial Kit | Lung Tissue Peptide Bioregulator 10 × 20 mg = 200 mg $260.00
$26.00 per vial
$1.30 Buy
Nexaph
#90 by metascore
Metascore 76Finnrick 57%PepIndex 19/100Bought vials 109% of label · 285 testsTitrateLab · PeptideBaseNo report for thisOnline checkout
Bronchogen 10mg (10 vials/kit) 10 × 10 mg = 100 mg $158.00
$15.80 per vial
$1.58 Buy
Eros Peptides
#129 by metascore · US, GA 30339
Metascore 74 medium confidenceFinnrick 77%Bought vials 110% of label · 3 testsTitrateLab · Peptide CriticLab report (image)Online checkout
Bronchogen 20MG 1 × 20 mg $33.99 $1.70 Buy
Amino Usa
#136 by metascore · US
Metascore 74 medium confidenceFinnrick 32%Bought vials 89% of label · 3 testsTitrateLabLab 99.7% pure · 102% of labelAccount needed
Bronchogen 20mg 1 × 20 mg $50.00 $2.50 Buy
Modern Aminos Affiliate
#125 by metascore · US
Metascore 75 medium confidenceFinnrick 79%PepIndex 81/100Bought vials 100% of label · 5 testsTitrateLab · PeptideBase · Peptide CriticNo report for thisOnline checkout
BRONCHOGEN 20MG
$30 off through this site's link (new customers)
1 × 20 mg $54.00
$30 off through this site's link (new customers)
$2.70 Buy
Lab Rat Peptide
#206 by metascore · US
Metascore 72 low confidenceFinnrick 76%TitrateLabNo public reportsOnline checkout
Bronchogen 20MG 1 × 20 mg $55.00 $2.75 Buy
Amino Asylum
#245 by metascore
Metascore 71Finnrick 62%PepIndex 26/100Bought vials 100% of label · 15 testsTitrateLab · PeptideBaseNo report for thisOnline checkout
Bronchogen 20MG 1 × 20 mg $64.99 $3.25 Buy
Core Peptides
#282 by metascore
Metascore 70 medium confidenceFinnrick 76%PepIndex 24/100Bought vials 92% of label · 4 testsTitrateLab · PeptideBase · Peptide Critic · PeptideCheckedLab 99.1% pureOnline checkout
Bronchogen – 20MG 1 × 20 mg $68.00 $3.40 Buy
Biolongevity Labs
#166 by metascore · US, Akron, OH 44321
Metascore 73Finnrick 71%PepIndex 58/100Bought vials 102% of label · 34 testsTitrateLab · Peptide CriticNo report for thisOnline checkout
Bronchogen (20mg) 1 × 20 mg $69.97 $3.50 Buy
Certified Peptides
#66 by metascore · US, WA 98579
Metascore 79Finnrick 58%Bought vials 100% of label · 12 testsTitrateLabNo report for thisOnline checkout
BRONNCHGEN 20MG 1 × 20 mg $105.00 $5.25 Buy
Amplified Amino Affiliate
#27 by metascore · US: TX 78248
Metascore 83Finnrick 65%Bought vials 115% of label · 12 testsTitrateLabNo report for thisOnline checkout
Bronchogen 10mg 1 × 10 mg $58.00 $5.80 Buy

Mixing a 20 mg vial

What each common amount of bacteriostatic water gives you on a U-100 insulin syringe. Pick a vial size above to change it.

WaterStrengthPer 10 units (0.1 mL)Per unit
1 mL20 mg/mL2,000 mcg200 mcg
2 mL10 mg/mL1,000 mcg100 mcg
3 mL6.667 mg/mL666.7 mcg66.67 mcg
5 mL4 mg/mL400 mcg40 mcg

Published lab results

5 certificates of analysis that vendors publish for Bronchogen. Numbers are only filled in where the document is readable text; image-only COAs are linked without numbers. A vendor's own COA shows one tested sample, not every batch.

VendorLabDateLabelMeasuredPurityBatch
Bulk Peptide SupplyCOA concerns
Most reports come from AV Analytics, a lab with no website or lookup to verify them, and they all read 99.73-99.81% purity across 19 different peptides and blends; its MDx reports are similarly uniform. Eight others are issued to 'Peptide COA Test LLC'. Checked 2026-10-08. How we check
AV Analytics2026-09-06 20 mg – 99.77% BRN208892 View
Ion Peptide
Freedom Diagnostics ✓ lab2026-09-05 20 mg 19.93 mg 100% 99.4% BRN20-09022026 View
Amino Usa
BioRegen2026-09-01 20 mg 20.47 mg 102% 99.71% 26BRON20-0005 View
Core Peptides
Vanguard Laboratory2026-08-21 20 mg – 99.1% C73555 View
Eros PeptidesCOA note
Janoshik– 20 mg – – View (image)

Doses studied in research Animal or lab studies only

What was given to people (or animals) in published studies and official labels, each linked to its source. This is not a recommendation: study products, purity and supervision differ from research-grade vials.

Animal studies: Rats with NO2-induced COPD-like lung damage received bronchogen for 1 month (dose not stated in the abstracts); tissue-culture studies used 0.05 ng/ml; other work is in cell lines, DNA and tobacco plants.

No human studies were found; nearly all research comes from the developer's group. Doses in animal studies do not translate directly to people.

What the research says

C
Mostly animal studies
Why: No human studies; two rat COPD-model studies from the developer's group plus cell, DNA and plant experiments.

Bronchogen (Ala-Glu-Asp-Leu, AEDL) is a St. Petersburg 'peptide bioregulator' marketed for the lungs; the evidence is two small rat COPD-model studies plus cell, DNA and even plant experiments, nearly all from the developer's network. No human studies were found.

Key papers ✓ 2? 3

  • ✓ Positive animalBull Exp Biol Med · 2015
    Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology.
    Animalssize not reported1 month of treatment
    Tetrapeptide Bronchogen therapy in a rat COPD model

    In rats with NO2-induced COPD-like lung damage, one month of Bronchogen reportedly reversed bronchial epithelial remodeling (goblet cell hyperplasia, metaplasia, emphysema), increased secretory IgA and reduced neutrophilic inflammation.

    Study details
    Studied
    Rats with COPD modeled by 60-day intermittent NO2 exposure
    Main outcome
    Bronchial epithelium remodeling, secretory IgA, cytokines
    Authors' conclusion
    One month of Bronchogen eliminated signs of bronchial epithelium and lung remodeling, raised secretory IgA and normalized cell composition and proinflammatory cytokines, reflecting reduced neutrophilic inflammation.
    Limitations
    Rat model; sample size not stated in abstract.
  • ✓ Positive animalRoss Fiziol Zh Im I M Sechenova · 2017
    [ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY].
    Animalssize not reported
    Bronchogen course with bronchoalveolar lavage analysis

    Same rat COPD model: Bronchogen normalized lavage-fluid cell composition and pro-inflammatory cytokines and raised secretory IgA and surfactant protein B.

    Study details
    Studied
    Rats with COPD modeled by 60-day intermittent nitrogen dioxide exposure
    Main outcome
    BALF cell composition, cytokines, secretory IgA, surfactant protein B
    Authors' conclusion
    Peptide treatment reduced neutrophilic inflammation, restored bronchial epithelium structure and increased secretory IgA and surfactant protein B.
    Limitations
    Rat model; sample size not stated in abstract.
  • ? Inconclusive in vitroBull Exp Biol Med · 2012
    Peptides tissue-specifically stimulate cell differentiation during their aging.
    Cells / lab
    In vitro expression study in young and late-passage (aging) cultures

    In aging human bronchial epithelial cell cultures, Bronchogen stimulated expression of differentiation factors CXCL12 and Hoxa3.

    Study details
    Studied
    Human embryonic pancreatic and bronchial cells and prostatic fibroblasts in culture
    Main outcome
    Expression of CXCL12, Hoxa3 and WEGC1 differentiation factors
    Authors' conclusion
    Vesugen stimulated differentiation factor expression in fibroblasts, with a stronger effect in aged cultures, which may be a mechanism of geroprotective effect.
    Limitations
    In vitro cell culture only.
  • ? Inconclusive in vitroBiochemistry (Mosc) · 2015
    Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
    Cells / lab
    In vitro gene expression and promoter DNA-methylation analysis with KEDW and AEDL peptides

    In aging bronchial cell cultures, AEDL altered expression of several lung genes (e.g. NKX2-1, SCGB1A1), possibly via promoter methylation changes; other genes were unaffected.

    Study details
    Studied
    Ageing human pancreatic and bronchial epithelium cell cultures
    Compared with
    Untreated cultures of different age
    Main outcome
    Gene expression and promoter methylation of PDX1, PAX6, NGN3 and other genes
    Authors' conclusion
    Changes in promoter methylation might explain the age- and peptide-induced changes in expression of PDX1, PAX6 and NGN3 in pancreatic cells; other genes appear controlled by other mechanisms.
    Limitations
    Cell cultures only; mechanism, not efficacy.
  • ? Inconclusive in vitroBull Exp Biol Med · 2011
    Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability.
    No new data
    Differential scanning microcalorimetry of DNA melting with bronchogen

    Calorimetry study: Bronchogen raised the melting temperature of isolated DNA by 3.1 °C, acting as a DNA-stabilizing agent.

    Key resultBronchogen increased the melting temperature of DNA by 3.1°C in a narrow range of molar ratios

    Study details
    Studied
    DNA from calf thymus and mouse liver
    Main outcome
    DNA melting temperature and enthalpy
    Authors' conclusion
    Bronchogen acts as a DNA-stabilizing agent, not specific for AT or GC pairs, binding strongly and occasionally to both strands.
    Limitations
    Biophysical in vitro study.

Reported side effects

No human safety or efficacy data in the published literature.

✓ positive · ✗ negative · ~ mixed · ? inconclusive, judged on each paper's own main outcome. Grades: A strong human evidence → D little or none. Papers and verdicts are drawn from PubMed, Europe PMC and Russian journals (CyberLeninka); not medical advice.

Discussions elsewhere

Experiences and questions about Bronchogen on other sites. Treat anecdotes with care.

Bronchogen: questions people ask

What is Bronchogen?

Russian short-peptide bioregulator. One of the Khavinson "bioregulator" peptides from Russian aging research, marketed for the bronchi and lungs. Evidence comes mainly from Russian cell and animal studies.

How much does Bronchogen cost?

The cheapest Bronchogen from an independently tested vendor is $0.750 per mg (Uther, Bronchogen 20mg (10 Vials / Kit), $150.00). Across 14 listings from 13 vendors the median is $2.70 per mg.

Where can I buy Bronchogen?

13 vendors tested by Finnrick sell Bronchogen. The cheapest per mg right now: Uther ($0.750), Qingdao Sigma Chemical QSC ($1.18), Bulk Peptide Wholesale ($1.25). 2 of them publish a lab report (COA) for Bronchogen; compare lab scores and reports in the table above before buying.

How much bacteriostatic water for 20 mg of Bronchogen?

Adding 2 mL of bacteriostatic water to a 20 mg vial of Bronchogen gives 10 mg/mL: each 10 units on a U-100 insulin syringe holds 1,000 mcg. With 1 mL it's 20 mg/mL (2,000 mcg per 10 units); with 3 mL, 6.667 mg/mL (666.7 mcg per 10 units). More water makes small amounts easier to measure. Mixing charts: 10 mg, 20 mg.

Is Bronchogen FDA approved?

Sold as a supplement in Russia; not approved in the US. Research use only.

Can Bronchogen be compounded in the US?

Not an FDA-approved drug and not nominated for FDA's 503A bulks list, so US pharmacies can't legally compound it. Compounding status for every peptide.

Does Bronchogen work? What does the research say?

Evidence grade C (mostly animal studies), from 5 papers: No human studies; two rat COPD-model studies from the developer's group plus cell, DNA and plant experiments. Bronchogen (Ala-Glu-Asp-Leu, AEDL) is a St. Petersburg 'peptide bioregulator' marketed for the lungs; the evidence is two small rat COPD-model studies plus cell, DNA and even plant experiments, nearly all from the developer's network. No human studies were found. See the papers.

What dose of Bronchogen was used in studies?

Bronchogen is tested only in animals or cells. Rats with NO2-induced COPD-like lung damage received bronchogen for 1 month (dose not stated in the abstracts); tissue-culture studies used 0.05 ng/ml; other work is in cell lines, DNA and tobacco plants. These are amounts used in published studies or official labels, not a recommendation.

More on Bronchogen