Eloralintide vs Retatrutide
Eloralintide: Amylin receptor agonist. Retatrutide: Triple GIP / GLP-1 / glucagon receptor agonist. Per milligram, Retatrutide is cheaper right now ($2.00 vs $0.350 at the cheapest tested vendor). Retatrutide has stronger published evidence (grade A vs B). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.
Eloralintide
A newer amylin-pathway compound studied on its own for weight loss, as an alternative or complement to GLP-1 drugs.
- What it is
- Amylin receptor agonist
- Category
- GLP-1 & metabolic
- Status
- Investigational (Eli Lilly, clinical trials). Not approved.
- Cheapest
- $2.00 per mg (Baohua Dongnuo Biotechnology BHD)
- Median price
- $5.40 per mg
- Vendors
- 13 independently tested, 2 with a lab report
- Research
- Grade B: Some human evidence (4 papers)
- Studied as
- studied in people
- Reported side effects
- Nausea (dose-dependent); Fatigue; Decreased appetite; Headache
Retatrutide
Adds glucagon-receptor activity, which raises energy expenditure, on top of the two incretin receptors. Phase 2 trials reported the largest average weight loss of any drug in its class so far.
- What it is
- Triple GIP / GLP-1 / glucagon receptor agonist
- Category
- GLP-1 & metabolic
- Status
- Investigational (Eli Lilly, Phase 3 trials). Not approved anywhere.
- Cheapest
- $0.350 per mg (Shanghai Wibson Biotechnology WBS)
- Median price
- $2.92 per mg
- Vendors
- 98 independently tested, 53 with a lab report
- Research
- Grade A: Strong human evidence (7 papers)
- Studied as
- studied in people
- Reported side effects
- Nausea, diarrhea, vomiting, constipation (dose-related, mostly mild-moderate); Increased heart rate; Hypersensitivity reactions (non-severe); Discontinuation due to adverse events
Questions people ask
What is the difference between Eloralintide and Retatrutide?
Eloralintide: Amylin receptor agonist. Retatrutide: Triple GIP / GLP-1 / glucagon receptor agonist. Per milligram, Retatrutide is cheaper right now ($2.00 vs $0.350 at the cheapest tested vendor). Retatrutide has stronger published evidence (grade A vs B). Prices per mg compare cost, not effect: the amounts used in studies differ between compounds.
Which is cheaper, Eloralintide or Retatrutide?
Retatrutide is cheaper per mg: $2.00 for Eloralintide vs $0.350 for Retatrutide at the cheapest independently tested vendor.